Around the 17th century, Wu San Gui overthrown the Mu Wang Palace with the help of a mysterious person, allowing them to do whatever they please to in Yun Nan, the Mu Wang Palace who had hidden in seclusion was massacred, and a simple youth named Jing Xiu Ming became the only survivor after being saved by the disciple of the Yunyou divine doctor named Ling Le Sui, but was infected with an illness that causes people to go berserk. In order to find the killer who killed his entire village and cure his illness, Jing Xiu Ming and Yunyou divine doctor’s disciple set off for a journey.